Injectable Microparticle Assembly
A breakthrough design for injectable microparticles was developed, published, and patented at MIT. Under a 2-year grant, the technology was to be transferred to the industrial lab of a small development company (PFH), where it was to be proven technically feasible ahead of additional investments toward commercialization. A major part of the effort was development of a novel approach to commercial manufacturing at full-scale (100MM vaccines per annum).
I was hired to generate the manufacturing plan. This included concept landscaping, process research and support of lab activities, concept down-selection, sub-contracted studies and process experiments, product cost modeling, and technical reporting.
Inadequacies of existing process:
•Oversized particle geometry
•Not injectable at scale
•Complex administration requirement
•Slow molding and sealing steps
•Micron-scale positioning
•Expensive manual processing
•Material waste
Product & Process Development
Feasibility, increased production, quality improvements, cost, user experience